Education
Wuhan University  B.S.  1986  Virology & Mol. Biology
Wuhan University  M.S.  1989  Biophysics
U. Texas Southwestern Medical Center  Ph.D.  1997  Biochem. & Mol. Biology
U. Texas at Dallas  M.S.  2000  Computer Science

Experience
1987 - 1989    Research Assistant, Institute of Microbiology, Academia Sinica, Beijing
1989 - 1992    Assistant Professor, Dept. of Virology, Wuhan University
1993 - 1997    Research Assistant, Dept. of Biochemistry, U. Texas Southwestern Medical School
1997 - 1998    Postdoctoral Fellow, Dept. of Biochemistry, U. Texas Southwestern Medical School
1998 - 1999    Software Engineer, PageMart Inc., Dallas, Texas
1999 - 2001    Bioinformatics Analyst, Large Scale Biology, Vacaville, California
2001 - 2003    Senior Scientist, Incyte Genomics, Inc., Palo Alto, California
2001 - 2002    Bioinformatics Instructor, Mos Institute of Technology, Santa Clara, California
2003 - 2004    Senior Scientist, Accelrys, Inc., San Diego, California
2004 - Present    Assistant Professor, Dept. of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina
1/2006-present   Member of Editorial Board, Computational Biology and Chemistry
3/2005-present   Member of Editorial Advisory Board, Current Bioinformatics

Research Interest
1) Biological information integration
2) Ontology development and integration
3) Genomics

Teaching
BMTRY 744: Introduction to Bioinformatics

Links:
 
My CV

Ontology Research
MUSC Biomedical Ontology Research Group
National Center for Ontological Research
National Center for Biomedical Ontology
GO
OBO

Software Engineering and Object-oriented technology
OMG
SEI

Publications:
Wenjin Zheng, Liangyi Kang, Guanying Qiu: Attenuation of the host symptom by CMV (Cucumber Mosaic Virus) satellite RNA (1-CARNA) is not related to the expression of viral coat protein,  Acta Agriculturae Nucleatae Sinica  6(2):111-115, 1992

Wenjin Zheng, H. Eric Xu and Stephen Albert Johnston: The cysteine peptidase, bleomycin hydrolase, is a new component of the galactose regulon in yeast.  J. Biological Chemistry  272: 30350-30355, 1997

Wenjin Zheng, Stephen A. Johnston, Leemor Joshua-Tor: The unique active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase and peptide ligase.  Cell  93: 103-109, 1998

Wenjin Zheng and Stephen A. Johnston: The nucleic acid binding activity of yeast bleomycin hydrolase is involved in bleomycin detoxification.  Molecular & Cellular Biology  18(6): 3580-3585, 1998

Paul A. O’Farrell, Fernando Gonzalez, Wenjin Zheng, Stephen Albert Johnston and Leemor Joshua-Tor:  Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.  Structure Fold Des.  7(6):619-627, 1999

Lisa Yan, Mikhail Velikanov, Paul Flook, Wenjin Zheng, Sándor Szalma, and Scott Kahn: Assessment of Putative Protein Targets Derived from the SARS Genome.  FEBS Letters.  554(3):257-63, 2003

W. Jim. Zheng, Velin Z. Spassov, Lisa Yan, Paul K. Flook and Sándor Szalma: A Hidden Markov Model with Molecular Mechanics Energy Scoring Function for Transmembrane Helix Prediction.  Computational Biology and Chemistry.  28(4):265-274, 2004

Daniel Shegogue and W. Jim Zheng: Capturing Biological Information with Class-Responsibility-Collaboration Cards.  Bioinformatics. 21(3):415-7, 2005

Daniel Shegogue and W. Jim Zheng: Object-oriented Biological System Integration: a SARS Coronavirus Example.  Bioinformatics.  21(10):2502-9, 2005

Daniel Shegogue and W. Jim Zheng: Integration of the Gene Ontology into an object-oriented architecture.  BMC Bioinformatics. 6(1):113 2005

W. Jim Zheng: Engineering Approaches toward Biological Information Integration at the Systems Level.  Current Bioinformatics. 1(1):85-93 2006

W. Jim Zheng: Book Review: Warren J. Ewens and Gregory Grant. Statistical Methods in Bioinformatics: An Introduction (2nd ed.), JASA, In press, 2006.

Linyong Mao and W. Jim Zheng: Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs.  BMC Bioinformatics. 7 (Suppl 4):S21, 2006

Lam C. Tsoi and W. Jim Zheng: A Method of Microarray Data Storage Using Array Data Type.  Computational Biology and Chemistry. 31(2):143.  2007

Jingshan Huang, Jiangbo Dang, Michael N. Huhns, W. Jim Zheng: Using Artificial Neural Network to Align Biological Ontology. BMC Genomics, 9: Suppl 2:S16, 2008

Sarah Bradshaw, W. Jim Zheng, Lam C. Tsoi, Gary S. Gilkeson, Xian K. Zhang: A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis. Clinical Immunology, 129(1):19-30. 2008

Hiroshi Kitagaki, Lauren A Cowart, Nabil Matmati, David Montefusco, Jason Gandy, Silvia Vaena de Avalos, Sergei A Novgorodov, Jim Zheng, Lina M Obeid, and Yusuf A Hannun: ISC1-Dependent Metabolic Adaptation Reveals an Indispensable Role for Mitochondria in Induction of Nuclear Genes During the Diauxic Shift in S. cerevisiae.  J. Biol. Chem., 2009, Accepted.

Lam C. Tsoi, Ravi Patel, Wenle Zhao, W. Jim Zheng: Text Mining Approach to Evaluate Terms for Ontology Development. J. Biomedical Informatics, 2009, Accepted

Lam C. Tsoi, Michael Boehnke, Richard Klein, W. Jim Zheng: Evaluation of Genome-wide Association Study Results through Development of Ontology Fingerprint. Bioinformatics, 2009, Accepted