Testis

Tumor Type

S1 Seminoma

S2 Classic

S3 Spermatocytic

S4 Anaplastic

S5 With trophoblastic giant cells

S6 Embryonal carcinoma

S7 Yolk sac tumor

S8 Mature teratoma

S9 Immature teratoma

S10 Embryonal carcinoma and teratoma (teratocarcinoma)

S11 Teratoma with malignant transformation

S12 Choriocarcinoma

S13 Mixed germ cell tumor composed of the following type(s):

Tumor Size

S14 The tumor greatest diameter is ___ cm

Intratubular Germ Cell Neoplasia (ITGCN)

S15 No ITGCN is identified

S16 ITGCN is present

Vascular Invasion

S17 No vascular invasion is identified

S18 Vascular invasion is present

Tunica Albuginea

S19 The tunica albuginea is free from tumor

S20 The tumor penetrates the tunica albuginea but does not perforate it

S21 The tumor perforates the tunica albuginea

Rete Testis

S22 The rete testis is free from tumor

S23 The rete testis is involved by tumor

Epididymis

S24 The epididymis is free from tumor

S25 The epididymis is involved by tumor

Spermatic Cord and Surgical Margins

S26 The spermatic cord (including its surgical margin) is free from tumor

S27 The spermatic cord if involved by tumor but its surgical margin is free

S28 The surgical margin of the spermatic cord is involved by tumor

Non-Neoplastic Testis

S29 The non-neoplastic testis shows no significant abnormalities

S30 The non-neoplastic testis shows the following abnormality(ies):

S31 Atrophy

S32 Fibrosis

S33 Chronic inflammation

Lymph Nodes

S34 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

S35 Right pelvic

S36 Right external iliac

S37 Right internal iliac

S38 Right periaortic

S39 Left pelvic

S40 Left external iliac

S41 Left internal iliac

S42 Left periaortic

Tumor Type

T1 Papillary carcinoma

T2 Classic type

T3 Follicular variant

T4 Solid/trabecular variant

T5 Microcarcinoma (occult sclerosing) variant

T6 Diffuse sclerosing variant

T7 Oncocytic (Hurthe cell) variant

T8 Tall cell variant

T9 Columnar cell variant

T10 Follicular carcinoma

T11 Hurthle cell carcinoma

T12 Poorly differentiated carcinoma, insular type

T13 Poorly differentiated carcinoma, ___ type

T14 Undifferentiated (anaplastic) carcinoma

T15 Without residual well-differentiated component

T16 With residual well-differentiated component of type

T17 Medullary carcinoma

T18 Classic type ___ type

T19 Mixed medullary-follicular carcinoma

Histologic Grade (for papillary, follicular, or Hurthle cell carcinoma only)

T20 Well differentiated

T21 Moderately differentiated

T22 Poorly differentiated

Mitotic Activity

T23 Mitotic activity is nil

T24 Mitotis activity is mild to moderate

T25 Mitotic activity is marked

Tumor Necrosis

T26 No tumor necrosis is identified

T27 Tumor necrosis is-focal

T28 Tumor necrosis is extensive

Other Tumor Features

T29 The tumor also exhibits the following feature(s):

T30 Squamous metaplasia

T31 Cytoplasmic clear cell changes

T32 Focal mucinous features

T33 Psammoma bodies

T34 Calcification of nonpsammoma type

T35 Marked stromal reaction

T36 Necrotic and/or reactive changes probably induced by the fine needle procedure

T37 Amyloid deposition

Tumor Location

T38 The tumor involves the right lobe

T39 The tumor involves the left lobe

T40 The tumor involves the isthmus

T41 The tumor involves the right lobe and isthmus

T42 The tumor involves the left lobe and isthmus

T43 The tumor involves both lobes and isthmus

Tumor Size

T44 The tumor greatest diameter is ___ cm

Encapsulation

T45 The tumor is totally surrounded by a fibrous capsule

T46 The tumor is partially surrounded by a fibrous capsule

T47 The tumor is not encapsulated

Capsular Invasion

T48 No evidence of capsular invasion is identified

T49 There is focal capsular invasion by tumor

T50 There is extensive capsular invasion by tumor

Blood Vessel Invasion

T51 No evidence of blood vessel invasion is identified

T52 Areas suggestive but not diagnostic of blood vessel invasion are present

T53 Focal vascular invasion is present

T54 Extensive vascular invasion is present

Extrathyroid Extension

T55 No evidence of extrathyroid extension is identified

T56 There is extrathyroid extension into

Thyroid-resection for carcinoma-cont'd

Surgical Margins

T57 All surgical margins are free from tumor

T58 The tumor is close (40X objective) to the following surgical margin(s):

T59 The tumor is present at the following surgical margin(s)

Tumor Multicentricity

T60 No evidence of tumor multicentricity is identified

T61 Gross multicentric foci of carcinoma are present

T62 Microscopic multicentric foci of carcinoma are present

C-Cell Hyperplasia (for medullary carcinoma cases only)

T63 No evidence of C-cell hyperplasia is present

T64 There is C-cell hyperplasia of mild to moderate degree

T65 There is C-cell hyperplasia of marked degree

T66 Presence of C-cell hyperplasia cannot be evaluated

Adenoma(s) (away from the carcinoma)

T67 No separate adenomas are identified

T68 Separate adenoma(s) is (are) identified

T69 Type:

T70 Number:

Non-Neoplastic Thyroid

T71 The non-neoplastic thyroid shows no abnormalities

T72 The non-neoplastic thyroid shows the following abnormality(ies):

T73 Nodular hyperplasia

T74 Lymphocytic thyroiditis

T75 Hashimoto's thyroiditis

T76 So-called palpation thyroiditis

T77 Atrophy

T78 Fibrosis

Parathyroid

T79 No parathyroid glands are identified

T80 The following parathyroid glands were identified:

[Specify number and, if possible, the site in parentheses]

T81 These parathyroid glands are not involved by carcinoma

T82 These parathyroid glands are involved by carcinoma

Lymph Nodes

T83 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

T84 Right submandibular (level I):

T85 Right upper jugular (level II):

T86 Right midjugular (level III):

T87 Right lower jugular (level IV):

T88 Right posterior cervical (level V):

T89 Right juxtathyroid (level VI):

T90 Right paratracheal and para-esophageal (level VII):

T91 Left submandibular (level I):

T92 Left upper jugular (level II):

T93 Left midjugular (level III):

T94 Left lower jugular (level IV):

T95 Left posterior cervical (level V):

T96 Left juxtathyroid (level VI):

T97 Left paratracheal and para-esophageal (level VII):

T98 Superior mediastinal:

T99 Pretracheal:

[For cases with metastatic lymph nodes, regardless of number or site]

T100 The size of the largest involved node is

T101 No perinodal (extracapsular) extension is identified

T102 Perinodal (extracapsular) extension is present

U1 No residual carcinoma

U2 No residual invasive carcinoma

Tumor Type

U3 In situ squamous cell carcinoma of uterine cervix

[Use only if there is NOT an invasive component]

U4 Superficially invasive squamous cell carcinoma of uterine cervix

U5 Large cell keratinizing

U6 Large cell nonkeratinizing

U7 Small cell

U8 Invasive squamous cell carcinoma of uterine cervix

U9 Large cell keratinizing

U10 Large cell nonkeratinizing

U11 Small cell

U12 In situ adenocarcinoma of uterine cervix [Use only if there is NO invasive component present]

U13 Invasive adenocarcinoma of uterine cervix

U14 NOS

U15 Mucinous

U16 Endometrioid

U17 Clear cell

U18 Mixed, composed of the following patterns:

U19 Invasive adenosquamous carcinoma of uterine cervix.

U20 Invasive neuroendocrine carcinoma of uterine cervix

Histologic Grade

U21 Well differentiated

U22 Moderately differentiated

U23 Poorly differentiated/undifferentiated

Depth of Invasion

U24 The maximal thickness of the cervical stromal invasion is ___ mm

U25 The thickness of the cervix in the area of maximal tumor invasion is ___ mm

U26 The maximal superficial spread of the tumor is ___ mm

[For superficially invasive squamous cell carcinoma only]

Tumor Multicentricity

U27 No evidence of tumor multicentricity is identified

U28 Multicentric foci of invasive carcinoma are present

In Situ Carcinoma (for cases also having an invasive component)

U29 No in situ carcinoma is identified

U30 In situ carcinoma is also present

Vascular Invasion

U31 No vascular invasion is identified

U32 Vascular invasion is present

Perineurial Invasion

U33 No perineurial invasion is identified

U34 Perineurial invasion is present

Vaginal Extension

U35 No vaginal extension is identified

U36 Vaginal extension is present

Uterine Corpus Extension

U37 The tumor does not extend into uterine corpus

U38 The tumor extends into the lower uterine segment (mucosa only)

U39 The tumor extends into the lower uterine segment (stroma only)

U40 The tumor extends into the lower uterine segment (mucosa and stroma)

U41 The tumor extends into the uterine fundus (endometrium only)

U42 The tumor extends into the uterine fundus (myometrium only)

U43 The tumor extends into the uterine fundus (endometrium and myometrium)

Parametrial Involvement

U44 No parametrial involvement is identified

U45 Parametrial involvement is present on the right side only

U46 Parametrial involvement is present on the left side only

U47 Parametrial involvement is.present bilaterally

Surgical Margins

U48 All surgical margins are free from tumor

U49 The following surgical margin(s) are involved by tumor:

U50 Deep cervical at

U51 Right parametrial

U52 Left parametrial

U53 Right and left parametrial

U54 Anterior va-inal

055 Posterior vaginal

U56 Anterior and posterior vaginal

Endometrium

U57 The endometrium is unremarkable

U58 The endometrium shows the following abnormality(ies):

U59 Atrophy

U60 Simple hyperplasia without atypia

U61 Simple hyperplasia with atypia

U62 Complex hyperplasia without atypia

U63 Complex hyperplasia with atypia

U64 Polyp(s)

U65 Radiation changes

Myometrium

U66 The myometrium is unremarkable

U67 The myometrium shows the following abnormality(ies):

U68 Adenomyosis

U69 Leiomyoma(s)

Adnexae

U70 All adnexae are unremarkable

U71 The right fallopian tube shows

U72 The right ovary shows

U73 The left fallopian tube shows

U74 The left ovary shows

U75 All other adnexae are unremarkable

Lymph Nodes

U76 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

U77 Right obturator:

U78 Right pelvic:

U79 Right external iliac:

U80 Right internal iliac:

U81 Right periaortic:

U82 Left obturator:

U83 Left pelvic:

U84 Left external iliac:

U85 Left internal iliac:

U86 Left periaortic:

V1 No residual endometrial carcinoma

Tumor Type

V2 Adenocarcinoma of endometrium

V3 Endometrioid type, NOS

V4 Endometrioid with squamous metaplasia (adenoacanthoma)

V5 Endometrioid, adenosquamous subtype

V6 Endometrioid, villoglandular subtype

V7 Clear cell type

V8 Papillary serous type

V9 Mixed type, composed of the following patterns:

V10 Malignant mixed mullerian tumor of endometrium

V11 With heterologous elements

V12 Without heterologous elements

Histologic Grade (for endometrioid types only)

V13 FIGO grade I (<_ 6% solid growth)

V14 FIGO grade 11(6%-50% solid growth)

V15 FIGO grade III (> 50% solid growth)

V16 FIGO grade not applicable

Nuclear Grade (for endometrioid types only)

V17 Nuclear grade 1

V18 Nuclear grade 2

V19 Nuclear grade 3

Depth of Invasion

V20 The tumor is limited to the endometrium

V21 The tumor invades to <=5 half of myometrium

V22 The tumor invades to > half of myometrium

V23 The maximal thickness of myorrietrial invasion is ___ mm [Important!]

V24 The thickness of the myometrium in the area of maximal tumor invasion is ___ mm [Important!]

Endocervical Invasion

V25 No endocervical invasion is identified `

V26 Endocervical invasion is present in the mucosa only

V27 Endocervical invasion is present in the stroma only

V28 Endocervical invasion is present both in the mucosa and the stroma

Vascular Invasion

V29 No vascular invasion is identified

V30 Vascular invasion is present

Endometrium

V31 The endometrium is unremarkable

V32 The endometrium shows the following abnormality(ies):

V33 Atrophy

V34 Simple hyperplasia without atypia

V35 Simple hyperplasia with atypia

V36 Complex hyperplasia without atypia

V37 Complex hyperplasia with atypia V38 Polyp(s)

V39 Radiation changes

Myometrium

V40 The myometrium is unremarkable

V41 The myometrium shows the following abnormality(ies):

V42 Adenomyosis

V43 Leiomyoma(s)

Adnexae

V44 All adnexae are unremarkable

V45 The right fallopian tube shows

V46 The right ovary shows

V47 The left fallopian tube shows

V48 The left ovary shows

V49 All other adnexae are unremarkable

Lymph Nodes

V50 The lymph node status is as follows (expressed as the number of metastasic nodes in relation to the total number of nodes examined):

V51 Right pelvic:

V53 Right external iliac;

V54 Right internal iliac:

V55 Right periaortic:

V56 Left obturator:

V57 Left pelvic:

V58 Left external iliac:

V59 Left internal iliac:

V60 Left periaortic:

For. Synchronous Ovarian and Endometrial Carciinomas of Similar Histology (If applicable):

V61 Note: The superficial character of the endometrial carcinoma suggests that it represents an independent primary rather than a metastasis from the ovarian carcinoma

W1 No residual carcinoma

W2 No residual invasive carcinoma

Tumor Type

W3 In situ squamous cell carcinoma [Use only if there is NOT an invasive component]

W4 Invasive squamous cell carcinoma

W5 Paget's disease

W6 Without invasive adenocarcinoma

W7 With invasive adenocarcinoma

Histologic Grade

WS Well differentiated

W9 Moderately differentiated

W10 Poorly differentiated/undifferentiated

Tumor Size

W11 The tumor length is ___ cm

W12 The tumor width is ___ cm

W13 The tumor maximal thickness is ___ cm

Tumor Location

W14 The tumor involves the following area(s):

W15 Right labius majus

W16 Left labius majus

W17 Right labius minus

W18 Left labius minus

W19 Clitoris

Vascular Invasion

W20 No vascular invasion is identified

W21 Vascular invasion is present

Perineurial Invasion

W22 No perineurial invasion is identified

W23 Perineurial invasion is present

Local Extension

W24 The tumor is limited to the vulva

W25 The tumor extends to the following adjacent area(s):

W26 Vagina

W27 Urethra

W28 Perineum

W29 Anus

Tumor Multicentricity

W30 No evidence of tumor multicentricity is identified

W31 Multicentric foci of invasive carcinoma are present

In Situ Carcinoma (for cases also having an invasive component)

W32 No in situ carcinoma is identified

W33 In situ carcinoma is also present

Surgical Margins

W34 All cutaneous, mucosal, and soft tissue margins are free from tumor

W35 The tumor involves the following surgical margin(s):

W36 Right cutaneous

W37 Left cutaneous

W38 Superior cutaneous

W39 Inferior cutaneous

W40 Perineal

W41 Anal

W42 Vaginal

W43 Urethral

W44 Soft tissue at

W45 All other margins are free from tumor

Non-Neoplastic Vulva

W46 The non-neoplastic vulva is unremarkable

W47 The non-neoplastic vulva shows the following abnormality(ies):

W48 Lichen sclerosus et atrophicus

W49 Keratosis without dysplasia

W50 Dysplasia of ___ degree

W51 Melanocytic nevus of ___ type

Lymph Nodes

W52 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):.

W53 Right inguinal:

W54 Right superficial inguinal:

W55 Right deep inguinal:

W56 Left inguinal:

W57 Left superficial inguinal:

W58 Left deep inguinal: