Lung

M1 No residual carcinoma

M2 No residual invasive carcinoma

Tumor Type

M3 In situ squamous cell carcinoma [use only if there is NOT an invasive component]

M4 Squamous cell carcinoma

M5 Spindle cell (sarcomatoid) carcinoma

M6 Adenocarcinoma

M7 N.O.S.

M8 Acinar type

M9 Papillary type

M10 Solid type

M11 Adenosquamous carcinoma

M12 Bronchiolo-alveolar carcinoma

M13 Giant cell carcinoma

M14 Large cell undifferentiated carcinoma

M15 Large cell neuroendocrine carcinoma

M16 Large cell carcinoma with neuroendocrine features

M17 Small cell undifferentiated carcinoma

M18 Oat cell type

M19 Intermediate cell type

M20 Atypical carcinoid tumor

M21 Carcinoid tumor

M22 Metastatic tumor, type

M23 The tumor is consistent with colorectal origin

M24 The tumor is consistent with ___ origin

M25 The number of metastases is

Histologic Grade

M26 Well differentiated

M27 Moderately differentiated

M28 Poorly differentiated/undifferentiated

Tumor Location

M29 Of right upper lobe

M30 Of right middle lobe

M31 Of right lower lobe

M32 Of left upper lobe

M33 Of left lower lobe

Tumor Size

M34 The tumor greatest diameter is <=3 cm

M35 The tumor greatest diameter is >3 cm

Vascular Invasion

M36 No vascular invasion is identified

M37 Vascular invasion is present.

Perineurial Invasion

M38 No perineurial invasion is identified

M39 Perineurial invasion is present

Mainstem Bronchus

M40 The mainstem bronchus is not involved by tumor

M41 The mainstem bronchus is involved by in situ carcinoma

M42 The mainstem bronchus is involved by invasive carcinoma

Bronchial Margin

M43 The bronchial margin is free from tumor

M44 The bronchial margin is involved by invasive carcinoma

Pleura

M46 The pleura is free from tumor

M47 The tumor extends subpleurally but not to the pleural surface

M48 The tumor involves the surface of the visceral pleura

M49 The tumor involves the chest wall

In Situ Carcinoma (for cases also having an invasive component)

M50 No in situ carcinoma is identified

M51 In situ carcinoma is also present

Non-Neoplastic Lung

M52 The non-neoplastic lung is unremarkable

M53 The non-neoplastic lung shows the following abnormality (ies):

M54 Focal obstructive pneumonitis

M55 Extensive obstructive pneumonitis

M56 Focal atelectasis

M57 Extensive stelectasis

M58 Emphysematous changes

M59 Interstitial fibrosis

Tumor Type

N1 Papillary serous tumor, borderline (low malignant potential)

N2 Papillary serous carcinoma

N3 Mucinous tumor, borderline (low malignant potential)

N4 Intestinal Subtype

NS Endocervical Subtype

N6 Mucinous carcinoma

N7 Endometrioid tumor, borderline (low malignant potential)

N8 Endometrioid carcinoma

N9 With squamous metaplasia

N10 Clear cell tumor, borderline (low malignant potential)

N11 Clear cell carcinoma

N12 Undifferentiated carcinoma

N13 Malignant mullerian mixed tumor

N 14 with heterologous elements

N15 without heterologous elements

N16 Mixed carcinoma, composed of the following components:

N17 Metastatic carcinoma of ___ type

N18 Consistent with origin

Histologic Grade

N19 Well differentiated

N20 Moderately differentiated

N21 Poorly differentiated/undifferentiated

Tumor Location

N22 The tumor is unilateral (right ovary)

N23 The tumor is unilateral (left ovary)

N24 The tumor is bilateral

For Unilateral Tumors Ovarian Surface

N25 The tumor does not involve the ovarian surface

N26 The tumor involves the ovarian surface

Residual Ovary

N27 There is no recognizable residual ovary

N28 The residual ovary shows no significant abnormalities

N29 The residual ovary shows the following abnormality (ies)

N30 Inclusion cyst(s)

N31 Endometriosis

N32 Treatment-related changes

Contralateral Ovary

N33 The contralateral ovary is not present

N34 The contralateral ovary shows no significant abnormalities

N35 The contralateral ovary shows the following abnormality(ies):

N36 Inclusion cyst(s)

N37 Endometriosis

N38 Treatment-related changes

N39 The tumor does not involve the ovarian surface on either side

N40 The tumor involves the ovarian surface on the right side

N41 The tumor involves the ovarian surface on the left - side

N42 The tumor involves the ovarian surface on the both sides

Residual Right Ovary

N43 There is no recognizable residual ovary on the right side

N44 The residual ovary on the right side shows no significant abnormalities

N45 The residual ovary on the right side shows the following abnormality (ies)

N46 Inclusion cyst(s)

N47 Endometriosis

N48 Treatment-related changes

Residual Left Ovary

N49 There is no recognizable residual ovary on the left side

N50 The residual ovary on the left side shows no significant abnormalities

N51 The residual ovary on the left side shows the following abnormality (ies)

N52 Inclusion cyst(s)

N53 Endometriosis

N54 Treatment-related changes

Right Fallopian Tube

N55 The right fallopian tube is unremarkable

N56 The right fallopian tube is involved by tumor

N57 The right fallopian tube shows

Left Fallopian Tube

N58 The left fallopian tube is unremarkable

N59 The left fallopian tube is involved by tumor

N60 The left fallopian tube shows

NOTE: If carcinoma is present in endometrium, stop here and continue with "Uterine Corpus" form

Endometrium

N61 The endometrium is unremarkable

N62 The endometrium shows the following abnormality(ies):

N63 Atrophy

N64 Simple hyperplasia without atypia

N65 Simple hyperplasia with atypia

N66 Complex hyperplasia without atypia

N67 Complex hyperplasia with atypia

N68 Polyp(s)

N69 Radiation changes

Myometrium

N70 The myometrium is unremarkable

N71 The myometrium shows the following abnormality(ies):

N72 Adenomyosis

N73 Leiomyoma(s)

Uterine Serosa

N74 The uterine serosa is unremarkable

N75 The uterine serosa is involved by the ovarian tumor

N76 The uterine serosa shows

Cervix

N77 The cervix is unremarkable

N78 The cervix shows chronic inflammation

N79 The cervix shows Lymph Nodes

N80 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

N81 Right obturator:

N82 Right pelvic:

N83 Right external iliac:

N84 Right internal iliac:

N85 Right periaortic:

N86 Left obturator:

N87 Left pelvic:

N88 Left internal iliac:

N90 Left periaortic:

O1 Invasive squamous cell carcinoma

O2 Verrucous carcinoma

O3 Spindle cell (sarcomatoid) carcinoma

O4 Spindle and giant cell carcinoma

O5 Mucoepidermoid carcinoma

O6 Adenocarcinoma

O7 Transitional cell carcinoma

Pattern of Growth

O8 The pattern of growth is superficially spreading

O9 The pattern of growth is vertical

O10 The pattern of growth is papillary

O11 The pattern of growth is multicentric

Histologic Grade

O12 Well differentiated

O13 Moderately differentiated

O14 Poorly differentiated/undifferentiated

Tumor Location

O15 The tumor involves the following anatomic site(s):

O16 Glans

O17 Foreskin

O18 Coronal sulcus

O19 Distal urethra

O20 Skin of shaft [Use if this is the only area of involvement]

Level of Invasion

O21 The tumor invades to the following level(s):

O22 Lamina propria

O23 Corpus spongiosum

O24 Corpora cavernosa

O25 Buck's fascia

O26 Preputial dartos

O27 Skin

Depth of Invasion

O28 The depth of invasion is ___ mm

Vascular Invasion

O29 No vascular invasion is identified

O30 Vascular invasion is present

Perineurial Invasion

O31 No perineurial invasion is identified

O32 Perineurial invasion is present

Tumor Satellitosis

O33 No evidence of tumor satellitosis is present

O34 Tumor satellitosis is present

Extrapenile Extension

O35 The tumor does not extend outside the penis

O36 The tumor extends to the following extrapenile site(s):

O37 Scrotum

O38 Testis

O39 Pubic skin

O40 Abdominal skin

O41 Skin of groin

Surgical Margins

O42 All surgical margins are free from either in situ or invasive carcinoma

O43 The following surgical margin(s) is (are) involved by invasive carcinoma:

O44 Urethra

O45 Skin of shaft

O46 Corpora cavernosa

O47 Foreskin

O48 All surgical margins are free from invasive carcinoma, but the following margin(s) is (are) involved by in situ carcinoma:

O49 Urethra

O50 Foreskin mucosa

O51 Skin of shaft

Tumor Multicentricity

O52 No evidence of tumor multicentricity is identified

O53 Multicentric foci of invasive carcinoma are present

In Situ Carcinoma (for cases also having an invasive component)

O54 No in situ carcinoma is identified

O55 In situ carcinoma is also present

Non-Neoplastic Mucosa

O56 The non-neoplastic mucosa is unremarkable

O57 The non-neoplastic mucosa shows the following abnormality (ies):

O58 Chronic inflammation 059 Fibrosis

O60 Balanitis xerotica obliterans

O61 Epithelial hyperplasia without dysplasia

O62 Dysplasia of ___ degree

O63 Condyloma

O64 Koilocytotic atypia

Lymph Nodes

O65 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

O66 Right sentinel:

O67 Right inguinal:

O68 Right superficial inguinal:

O69 Right deep inguinal:

O70 Right pelvic:

O71 Left sentinel:

O72 Left inguinal:

O73 Left superficial inguinal:

O74 Left deep inguinal:

O75 Left pelvic:

[For cases with metastatic lymph nodes, regardless of number or site]:

O76 The size of the largest involved node is

O77 No perinodal (extracapsular) extension is identified

O78 Perinodal (extracapsular) extension is present

P1 No residual carcinoma

Tumor Type

P2 Adenocarcinoma of prostate

Histologic Grade

P3 Well differentiated

P4 Moderately differentiated

P5 Poorly differentiated/undifferentiated Gleason's Grade

P6 Gleason's grade is __ + __ / 10

Tumor Location

P7 The tumor involves the following quadrant(s):

P8 Right posterior

P9 Right anterior

P10 Left posterior

P11 Left anterior Vascular Invasion

P12 No vascular invasion is identified

P13 Vascular invasion is present Perineurial Invasion

P14 No perineurial invasion. is identified

P15 Vascular invasion is present Tumor Multicentricity

P16 No evidence of tumor multicentricity is identified

P17 Multicentric foci of invasive carcinoma are present

Staging

P18 The tumor is confined to the prostate and involves half of a lobe or less (stage pT2a)

P19 The tumor is confined to the prostate and involves more than half a lobe but not both lobes (stage pT2b)

P20 The tumor is confined to the prostate and involves both lobes (stage pT2c)

P21 The tumor invades into the prostatic apex

P22 The tumor invades into the prostatic capsule but not beyond

P23 The tumor exhibits unilateral extracapsular extension (stage pT3a)

P24 The tumor exhibits bilateral extracapsular extension (stage pT3b)

P25 The tumor invades into the right seminal vesicle (stage pT3c)

P26 The tumor invades into the left seminal vesicle (stage pT3c)

P27 The tumor invades into both seminal vesicles (stage pT3c)

P28 The tumor invades into bladder neck (stage pT4a)

Surgical Margins

P29 All surgical margins are free from tumor

P30 Tumor is present at the following surgical margin(s):

P31 Apical (urethral)

P32 Soft tissue [specify site]

P33 Bladder neck

Presence of PIN

P34 No evidence of PIN is identified

P35 There is focal PIN (<_ 2 foci)

P36 There is multifocal PIN (> 3 foci)

Location of PIN

P37 The PIN is adjacent to the adenocarcinoma

P38 The PIN is both adjacent and away from the adenocarcinoma

P39 The PIN is away from the adenocarcinoma

Non-Neoplastic Prostate

P40 The non-neoplastic prostate is unremarkable

P41 The non-neoplastic prostate shows the following abnormality(ies):

P42 Nodular hyperplasia

P43 Chronic prostatitis

P44 Infarct

P45 Basal cell hyperplasia

Prostate-radical prostatectomy for carcinoma-cont'd

Lymph Nodes

P46 The lymph node status is as follows (expressed as the number of metastasic nodes in relation to the total number of nodes examined):

P47 Right pelvic:

P48 Right internal iliac:

P49 Right external iliac:

P50 Right periaortic:

P51 Left pelvic:

P52 Left internal iliac:

P53 Left external iliac:

P54 Left periaortic:

Lymph Node Staging

P55 No regional lymph node metastases are identified (pNO)

P56 There is metastasis in a single lymph node, 2 cm or less in greatest dimension (pN1)

P57 There is metastasis in a single lymph node, more than 2 cm but no more than 5 cm in greatest dimension, or in multiple lymph nodes, none more than 5 cm in greatest dimension (pN2)

P58 There is metastasis in one or more lymph nodes, more than 5 cm in greatest dimension (pN3)

Diagnosis:

Q1 No residual malignant melanoma

Tumor Type

Q2 Malignant melanoma

Level and Depth

Q3 Clark's level

Q4 Depth of invasion mm

Radial Growth Phase

Q5 No radial growth phase is identified

Q6 Radial growth phase is present, superficial spreading type

Q7 Radial growth phase is present, lentigo maligna type

Q8 Radial growth phase is present, acral lentiginous type

Q9 Radial growth phase is present, undetermined type

Q10 Radial growth phase cannot be evaluated

Vertical Growth Phase

Q11 No vertical growth phase is identified

Q12 Vertical growth phase is present, epithelioid type

Q13 Vertical growth phase is present, spindle cell type

Q14 Vertical growth phase is present, mixed cell type

Q15 Vertical growth phase cannot be evaluated

Ulceration

Q16 No ulceration is identified

Q17 Ulceration is present, ___ mm wide

Q18 Ulceration cannot be evaluated

Pigmentation

Q19 No pigmentation is identified

Q20 Pigmentation is mild to moderate

Q21 Pigmentation is marked

Lymphoid Response at Base (TIL)

Q22 No lymphoid response at base (TIL) is identified

Q23 Lymphoid response at base (TIL) is mild (nonbrisk)

Q24 Lymphoid response at base (TIL) is marked (brisk)

Q25 Lymphoid response at base (TIL) cannot be evaluated

Signs of Regression

Q26 No signs of regression are identified

Q27 Signs of regression are present

Q28 Signs of regression cannot be evaluated

Associated Melanocytic Nevus

Q29 No evidence of an associated melanocytic nevus is identified

Q30 There is an associated melanocytic nevus, ___ type

Vascular Invasion

Q31 No vascular invasion is identified

Q32 Vascular invasion is present

Q33 Vascular invasion cannot be evaluated

Microscopic Satellitosis

Q34 No microscopic satellitosis is identified

Q35 Microscopic satellitosis is present

Q36 Microscopic satellitosis cannot be evaluated

Lateral Margins of Excision

Q37 The lateral margins of excision are free from tumor

Q38 The lateral margins of excision are involved by tumor

Q39 The lateral margins of excision cannot be evaluated

Deep Margins of Excision

Q40 The deep margins of excision are free from tumor

Q41 The deep margins of excision are involved by tumor

Q42 The deep margins of excision cannot be evaluated

Non-Neoplastic Skin

Q43 The non-neoplastic skin is unremarkable

Q44 The non-neoplastic skin shows the following abnormality(ies):

Q45 Actinic keratosis

Q46 Melanocytic hyperplasia

Q47 Anatomically separate melanocytic nevus(i) of ___ type

Lymph Nodes

Q48 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):

[For cases with metastatic lymph nodes, regardless of number or site]:

Q49 The size of the largest involved node is

Q50 No perinodal (extracapsular) extension is identified

Q51 Perinodal (extracapsular) extension is present

Diagnosis:

R1 No residual carcinoma

R2 No residual invasive adenocarcinoma

Tumor Type

R3 In situ carcinoma [use only if there is NOT an invasive component]

R4 Invasive adenocarcinoma

R5 Tubular (intestinal) R6 Papillary

R7 Signet ring

R8 Mucinous (non-signet ring)

R9 With neuroendocrine features

R10 With squamous metaplasia (adenosquamous carcinoma)

Histologic Grade

R11 Well differentiated

R12 Moderately differentiated

R13 Poorly differentiated/undifferentiated

Location

R14 Of upper third (cardiac area/fundus)

R15 Of middle third (corpus)

R16 Of lower third (antral area/pylorus)

Tumor Size

R17 The tumor length is ___ cm

R18 The tumor width is ___ cm

R19 The tumor maximal thickness is ___ cm

Pre-existing Polyp (at the site of the carcinoma)

R20 No evidence of a pre-existent polyp is identified

R21 There is evidence of a pre-existing polyp of ___ type

Local Invasion

R22 The tumor in noninvasive (pTis)

R23 The tumor invades into the lamina propria (pTI)

R24 The tumor invades into the submucosa (pTI)

R25 The tumor invades into the muscularis propria (pT2)

R26 The tumor invades into the subserosa (pT2)

R27 The tumor invades at the serosal surface (pT3)

R28 The tumor invades into the following adjacent structure(s) (pT4):

Vascular Invasion

R29 No vascular invasion is identified

R30 Vascular invasion is present

Perineurial Invasion

R31 No perineurial invasion is identified

R32 Perineurial invasion is present

Spleen

R33 The spleen was not resected

R34 The spleen is not involved by tumor

R35 The spleen shows direct invasion by tumor

R36 The spleen shows metastatic tumor

Pancreas

R37 The pancreas was not resected

R38 The pancreas is not involved by tumor

R39 The pancreas shows direct invasion by tumor

R40 The pancreas shows metastatic tumor

Peritoneum

R41 No peritoneal tumor implants are identified

R42 There are peritoneal tumor implants

Surgical Margins

R43 All surgical margins are free from tumor

R44 Tumor is present at the following surgical margin(s):

In Situ Carcinoma (for cases also having an invasive component)

R45 No in situ carcinoma is identified

R46 In situ carcinoma is also present

Polyps (away from the carcinoma)

R47 No separate polyps are identified

R48 Separate polyp(s) is(are) present:

R49 Type:

R50 Number:

Non-Neoplastic Stomach

R51 The non-neoplastic stomach is unremarkable

R52 The non-neoplastic stomach shows the following abnormality(ies):

R53 Dysplasia of ___ degree

R54 Chronic atrophic gastritis of ___ degree

R55 without intestinal metaplasia

R56 with intestinal metaplasia

R57 Superficial gastritis

R58 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):