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G1 No residual carcinoma G2 No residual invasive carcinoma Tumor Type G3 In situ squamous cell carcinoma [Use only if there is NOT an invasive component]
G4 Invasive squamous cell carcinoma G5 In situ adenocarcinoma [Use only if there is NOT an associated component] G6 Invasive adenocarcinoma G7 Invasive basaloid squamous cell carcinoma Histologic Grade (for invasive tumors only) G8 Well differentiated G9 Moderately differentiated G10 Poorly differentiated/undifferentiated Tumor Location G11 Of upper third of esophagus G12 Of middle third of esophagus G13 Of lower third of esophagus G14 Of gastro-esophageal junction
Tumor Size
G15 The tumor length is ___ cm G16 The tumor width is ___ cm G17 The tumor maximal thickness is ___ cm
Staging
G18 The tumor does not invade the stroma (Tis) G19 The tumor invades into the submucosa (T1) G20 The tumor invades into the muscularis propria (T2) G21 The tumor invades into the adventitia (T3) G22 The tumor extends into the following adjacent structure(s) (T4):
Vascular Invasion
G23 No vascular invasion is identified G24 Vascular invasion is present
Perineurial Invasion
G25 No perineurial invasion is identified G26 Perineurial invasion is present Tumor Multicentricity G27 No evidence of tumor multicentricity is identified G28 Multicentric foci of invasive carcinoma are present In Situ Carcinoma (for cases also having an invasive component)
G29 No in situ carcinoma is identified G30 In situ carcinoma is also present
Non-Neoplastic Mucosa
G31 The non-neoplastic mucosa is unremarkable G32 The non-neoplastic mucosa shows chronic inflammation of ___ degree G33 The non-neoplastic mucosa shows dysplasia of degree G34 The adjacent mucosa shows Barrett's esophagus of type G35 without evidence of dysplasia G36 with dysplasia of degree Proximal Margin G37 The proximal margin is separated from the carcinoma by a distance of ___ cm G38 The proximal margin is involved by in situ carcinoma G39 The proximal margin is involved by invasive carcinoma
Distal Margin
G40 The distal margin is separated from the carcinoma by a distance of ___ cm G41 The distal margin is involved by in situ carcinoma G42 The distal margin is involved by invasive carcinoma
Deep Margin
G43 The deep margin is free from carcinoma G44 The deep margin is involved by carcinoma Lymph Nodes G45 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined):
[For cases with metastatic lymph nodes, regardless of number or site]:
G46 The size of the largest involved node is G47 No perinodal (extracapsular) extension is identified G48 Perinodal (extracapsular) extension is present H1 Renal cell carcioma H2 Clear cell type H3 Granular cell type H4 Clear and -ranular cell type H5 Spindle cell (sarcomatoid) type H6 Chromophobe cell type H7 Oncocytoma H8 Transitional cell carcinoma of renal pelvis H9 with focal glandular metaplasia H10 with focal squamous metaplasia
Nuclear Grade (for renal cell carcinoma only)
H11 Nuclear grade I/IV H12 Nuclear grade II/IV H13 Nuclear grade III/IV H14 Nuclear grade IV/IV
Histologic Grade (for renal pelvic tumors only)
H15 Well differentiated H16 Moderately differentiated H17 Poorly differentiated/undifferentiated
Pattern of Growth (for renal cell carcinoma only)
H18 The pattern of growth is acinar H19 The pattern of growth is papillary H2O The pattern of growth is papillary and acinar H21 The pattern of growth is papillary and tubular H22 The pattern of growth is solid
Tumor Size
H23 The tumor greatest diameter is ___ cm Local Invasion H24 The tumor is confined within the renal capsule H25 The tumor extends through the renal capsule but is confined within Gerota's fascia H26 The tumor extends-into the renal pelvis [for renal cell carcinoma only]
Renal Vein Invasion
H27 No invasion of the renal vein is identified H28 Invasion of the renal vein is present
Surgical Margins
H29 All surgical margins are free from tumor H30 The tumor involves the following surgical margin(s): H31 Ureteral margin H32 Renal vein H33 Soft tissue H34 Renal parenchymal [for partial nephrectomy specimens only]
Non-Neoplastic Kidney
H35 The non-neoplastic kidney is unremarkable H36 The non-neoplastic kidney shows Adrenal Gland H37 The adrenal gland is not submitted/not identified H38 The adrenal gland is unremarkable H39 The adrenal gland is involved by tumor by direct extension H40 The adrenal gland is involved by metastatic carcinoma H41 The adrenal gland shows
Lymph Nodes
H42 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined): H43 Renal hilar: H44 Right retroperitoneal: H45 Left retroperitoneal:
I1 No residual carcinoma
Tumor Type
I2 Adenocarcinoma I3 NOS without mucinous component I4 NOS with mucinous component representing <= 50% of the tumor I5 With >50% mucinous component (so-called mucinous carcinoma) I6 Signet ring carcinoma I7 Adenosquamous carcinoma I8 Small cell undifferentiated carcinoma
Histologic Grade
I9 Well differentiated I10 Moderately differentiated I11 Poorly differentiated/undifferentiated
Tumor Location
I12 Of cecum I13 Of ascending colon I14 Of hepatic flexure I15 Of transverse colon I16 Of splenic flexure I17 Of descending colon I18 Of sigmoid colon I19 Of rectosigmoid I20 Of rectum
Gross Configuration
I21 The gross configuration is polypoid I22 The gross configuration is fungating I23 The gross configuration is plaque-like I24 The gross configuration is annular (constrictive) I25 The gross configuration is ulcerating infiltrative I26 The gross configuration is diffuse (linitis plastica type) I27 The cross configuration is
Pre-existing Polyp (At the site of the carcinoma)
I28 No evidence of a pre-existing polyp is identified I29 There is evidence of a pre-existing polyp of ___ type
Tumor Size
I30 The tumor length is ___ cm I31 The tumor width is ___ cm I32 The tumor maximal thickness is ___ cm
Local Invasion
I33 The tumor is noninvasive (pTis) I34 The tumor invades into the lamina propria (pTis) I35 The tumor invades into the submucosa (pTI) I36 The tumor invades into the muscularis propria (pT2) I37 The tumor invades into the subserosa or into the nonperitonealized pericolic or perirectal tissue (pT3) I38 The tumor invades into the following adjacent structure(s) (pT4):
Tumor Perforation
I39 No gross tumor perforation is identified I40 There is gross tumor perforation
Free Serosal Surface (for colonic tumors only)
I41 The free serosal surface is not involved by tumor I42 The free serosal surface is involved by tumor Vascular Invasion I43 No vascular invasion is identified I44 Vascular invasion is present Perineurial Invasion I45 No Perineurial invasion is identified I46 Perineurial invasion is present Surgical Margins I47 All surgical margins are free from tumor I48 Tumor is present at the following surgical margin(s):
Distance from Pectinate Line (for rectal tumors only)
I49 The distance between the tumor and the pectinate line is ___ cm
Polyps (away from the carcinoma)
I50 No separate polyps are identified I51 Separate polyp(s) is (are) present I52 Type: I53 Number:
Non-Neoplastic Bowel
I54 The non-neoplastic bowel is unremarkable I55 The non-neoplastic bowel shows the following abnormality (ies): I56 Ulcerative colitis with dysplasia I57 Ulcerative colitis without dysplasia I58 Diverticula
Large bowel-colectomy for carcinoma-cont'd
Lymph Nodes
I59 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined): I60 Pericolic or perirectal I61 Along the course of a named vascular trunk
Lymph Node Staging
I62 No regional lymph node metastases are identified (pNO) I63 There are metastases in 1 to 3 pericolic or perirectal lymph nodes (pNI) I64 There are metastases in 4 or more colic or perirectal lymph nodes (pN2) I65 There are metastases in 1 or more lymph nodes along course of a major named vascular trunk (pN3)
Larynx-partial or total laryngectomy for carcinoma
Diagnosis:
J1 No residual carcinoma J2 No residual invasive carcinoma
Tumor Type
J3 In situ squamous cell carcinoma [Use only if there is NOT an invasive component] J4 Invasive squamous cell carcinoma J5 Verrucous carcinoma J6 Basaloid squamous cell carcinoma J7 Spindle cell (sarcomatoid) carcinoma J8 Adenocarcinoma of minor salivary gland origin, type J9 Neuroendocrine carcinoma, small cell type J10 Neuroendocrine carcinoma, large cell type
Histologic Grade
J11 Well differentiated J12 Moderately differentiated J13 Poorly differentiated/undifferentiated Tumor Size J14 The tumor greatest diameter is J15 The tumor maximal thickness is Tumor Location J16 The primary tumor location is the supraglottis [specify site] J17 The primary tumor location is the glottis [specify site] J18 The primary tumor location is the infraglottis [specify site]
Local Extension
J19 No local extension is identified J20 There is local extension into the following site(s): J21 Commissure J22 Ventricle J23 Right false vocal cord J24 Left false vocal cord J25 Subglottis Stromal Invasion J26 No evidence of stromal invasion is identified (Tis) J27 There is stromal invasion into the following structure(s): J28 Lamina propria J29 Muscle J30 Cartilage ( ) [specify] J31 Perilaryngeal soft tissues
Vascular Invasion
J32 No vascular invasion is identified J33 Vascular invasion is present Perineurial -Invasion J34 No perineurial invasion is identified J35 Perineurial invasion is present
Tumor Multricentricity
J36 No evidence of tumor multicentricity is identified J37 Multicentric foci of invasive carcinoma are present
In Situ Carcinoma (for cases also having an invasive component)
J38 No in situ carcinoma is identified J39 In situ carcinoma is also present
Non-Neoplastic Mucosa
J40 The non-neoplastic mucosa is unremarkable J41 The non-neoplastic mucosa shows keratosis without dysplasia J42 The non-neoplastic mucosa shows dysplasia of degree
Surgical Margins
J43 All surgical margins are free from tumor J44 The tumor involves the following surgical margin(s):
Larynx--partial or total laryngectomy for carcinoma-cont'd
Lymph Nodes
J45 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined): J46 Right submandibular (level I): J47 Right upper jugular (level II): J48 Right midjugular (level III): J49 Right lower jugular (level IV): J50 Right posterior cervical (level V): J51 Right juxtathyroid (level VI): J52 Right paratracheal and para-esophageal (level VII): J53 Left submandibular (level I): J54 Left upper jugular (level II): J55 Left midjugular (level III): J56 Left lower jugular (level IV): J57 Left posterior cervical (level V): J58 Left juxtathyroid (level VI): J59 Left paratracheal and para-esophageal (level VII):
[For cases with metastatic lymph nodes, regardless of number or site]:
J60 The size of the largest involved node is J61 No perinodal (extracapsular) extension is identified J62 Perinodal (extracapsular) extension is present Kl No residual carcinoma K2 No residual invasive carcinoma
Tumor Type
K3 In situ squamous cell carcinoma [use only if there is NOT an invasive component] K4 Invasive squamous cell carcinoma K5 Verrucous carcinoma K6 Spindle cell (sarcomatoid) carcinoma K7 Adenosquamous carcinoma K8 Basaloid squamous cell carcinoma K9 Small cell carcinoma K10 Adenocarcinoma of minor salivary gland origin, type
Histologic Grade
K11 Well differentiated K12 Moderately differentiated K13 Poorly differentiated/undifferentiated
Tumor Size
K14 The tumor greatest diameter is ___ cm. K15 The tumor maximal thickness is ___ cm Tumor Location K16 The tumor location is: K17 Lower lip K18 Upper lip K19 Floor of mouth K20 Oral tongue K21 Base of the tongue K22 Upper gingiva K23 Lower gingiva K24 Buccal mucosa (inner surface of cheek) K25 Hard palate K26 Soft palate K27 Retromolar trigone ( ___ side) K28 Anterior tonsillarpillar ( ___ side) K29 Tonsillar fossa ( ___ side) K30 Posterior tonsillar pillar ( ___ side) K31 Pyriform sinus ( ___ side) K32 Pharyngeal wall
Midline Extension
K33 No extension across the midline is identified K34 The tumor extends across the midline
Tumor Invasion Within the Oral Cavity
K35 No stromal invasion is present (Tis) K36 The tumor invades the following structure(s): K37 Lamina propria K38 Superficial muscle of tongue K39 Skeletal muscle [do NOT use for tongue tumors] Tumor Invasion of Adjacent Structures K40 The tumor does not invade adjacent structures K41 The tumor invades the following adjacent structure(s): K42 Deep muscle of tongue K43 Periosteum K44 Cortical bone K45 Maxillary sinus K46 Skin K47 Larynx [specify site] Tumor Necrosis K48 No tumor necrosis is identified K49 Tumor necrosis is minimal K50 Tumor necrosis is extensive Vascular Invasion K51 No vascular invasion is identified K52 Vascular invasion is present Perineurial Invasion K53 No perineurial invasion is identified K54 Perineurial invasion is present Tumor Multicentricity K55 No evidence of tumor multicentricity is identified K56 Multicentric foci of invasive carcinoma are present
In Situ Carcinoma (for cases also having an invasive component)
K57 No in situ carcinoma is identified K58 In situ carcinoma is also present Non-Neoplastic Mucosa K59 The non-neoplastic mucosa shows no significant abnormalities K60 The non-neoplastic mucosa shows the following abnormality(ies) K61 Dysplasia of ___ degree K62 Keratosis without dysplasia K63 Atypia, consistent with radiation changes K64 Chronic inflammation
Lip, oral cavity or oropharynx-resection for carcinoma-cont'd
Surgical Margins K65 All surgical margins are free from invasive or in situ carcinoma K66 All surgical margins are free from invasive carcinoma K67 Invasive tumor is present at the following margin(s): K68 Invasive tumor is close (40X objective) to the following margin(s): K69 In situ carcinoma is present at the following margin(s): K70 In situ carcinoma is close (40X objective) to the following margin(s):
Lymph Nodes
K71 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined): K72 Right submental (level I): K73 Right submandibular (level I): K74 Right upper jugular (level II): K75 Right midjugular (level III): K76 Right lower jugular (level IV): K77 Right posterior cervical (level V): K78 Right juxtathyroid (level VI): K79 Right paratracheal and para-esophageal (level VII): K80 Left submental (level I): K81 Left submandibular (level I): K82 Left upper jugular (level II): K83 Left midjugular (level III): K84 Left lower jugular (level IV): K85 Left posterior cervical (level V): K86 Left juxtathyroid (level VI): K87 Left paratracheal and para-esophageal (level VII): K88 Pretracheal:
(For cases with metastatic lymph nodes, regardless of number or site]:
K89 The size of the largest involved node is K90 No perinodal (extracapsular) extension is identified K91 Perinodal (extracapsular) extension is present
Tumor Type
L1 Hepatocellular carcinoma, type L2 Cholangiocarcinoma L3 Of extrahepatic bile ducts L4 Of intrahepatic bile ducts L5 Mixed hepatocellular carcinoma/cholangiocarcinoma L6 Hepatoblastoma L7 Epithelial type (embryonal subtype) L8 Epithelial type (fetal subtype) L9 Epithelial type (embryonal and fetal subtypes) L10 Epithelial and mesenchymal type (mixed) L11 Metastatic tumor, adenocarcinoma type L12 Metastatic tumor, ___ type L13 The tumor is consistent with colorectal origin L14 The tumor is consistent with ___ origin L15 The number of metastases is
Histologic Grade
L16 Well differentiated L17 Moderately differentiated L18 Poorly differentiated/undifferentiated Tumor Size L19 The greatest tumor diameter is ___ cm L20 The greatest diameter of the largest tumor is ___ cm
Tumor Capsule
L21 The tumor is not encapsulated L22 The tumor is partially surrounded by a fibrous capsule L23 The tumor is completely surrounded by a fibrous capsule
Tumor Necrosis
L24 The approximate amount of tumor necrosis is
Vascular Invasion
L25 No Vascular invasion is identified L26 Vascular invasion is present in the following form(s): L27 As involvement of the portal vein L28 As involvement of branches of the portal vein L29 As tumor thrombi in small vessels
Perineurial Invasion
L30 No perineurial invasion is identified L31 Perineurial invasion is present
Multifocality (for primary tumors only)
L32 No satellites or multiple tumor foci are identified L33 Satellite tumor nodules are present L34 The tumor is multifocal
Hepatic Capsule
L35 The hepatic capsule is free from tumor L36 The tumor is present beneath the hepatic capsule but not on the surface L37 The tumor is present on the hepatic capsular surface
Local Extension (for liver tumors only)
L38 The tumor is confined to the liver L39 The tumor invades the following extrahepatic structure(s):
Local Extension (for tumors of extrahepatic bile ducts only)
L40 The tumor is confined to the bile duct wall L41 The tumor extends into periductal soft tissues Hepatic Surgical Margins L42 The surgical margins are free from tumor L43 The tumor gross clearance is ___ cm L44 The tumor microscopic clearance is ___ cm L45 The surgical margins are involved by tumor
Distal Bile Duct Margin
L46 The distal bile duct margin is free from tumor L47 The distal bile duct margin is involved by tumor
Non-Neoplastic Liver
L48 The non-neoplastic liver is unremarkable L49 The non-neoplastic liver shows the following abnormality(ies): L50 Peritumoral fibrosis L51 Cirrhosis of ___ type L52 Hepatitis of ___ type L53 Steatosis of ___ degree L54 Hepatocytic dysplasia
Lymph Nodes L55 The lymph node status is as follows (expressed as the number of metastatic nodes in relation to the total number of nodes examined): |
