John Arthur, MD, PhD

Medical University of South Carolina
Division of Nephrology
 96 Jonathan Lucas, 829 CSB, PO Box 250623
Charleston, SC 29425-2220

Telephone:     (843) 792-4123
Fax:                   (843) 792-8399

E-mail address: arthurj@musc.edu

Education

Johnston High School                                                                                1978
             Johnston, Iowa
Iowa State University                                                                                 1983, B.S. Zoology
             Ames, Iowa                                                                                    (with distinction)
University of Iowa                                                                                      1990, M.D.
            
College of Medicine
             Iowa City, Iowa
University of Iowa                                                                                      1990, Ph.D.
            
Department of Pharmacology               Dissertation title:  Studies on the              participation of the coronary circulation in the defense reaction.
            
Iowa City, Iowa                                       Advisor: Michael J. Brody, Ph.D.


Postgraduate training

Intern in Internal Medicine                                                                        1990-1991                     Duke University Medical Center, Durham, North Carolina                              
Clinical Resident in Internal Medicine                                                    1991-1992                     Duke University Medical Center, Durham, North Carolina
Research Resident in Internal Medicine                                                1992-1994                     Duke University Medical Center, Durham, North Carolina                              
             Clinical Investigator Pathway
             Mentor: John R. Raymond, M.D.
Clinical Fellow in Nephrology                                                                   1994-1995                     Duke University Medical Center, Durham, North Carolina                 
Research Fellow in Nephrology                                                              1995-1996                     Duke University Medical Center, Durham, North Carolina
             Mentor: John R. Raymond, M.D.

Appointments

American Heart Association Medical Student Research Fellow                                                            1984-85
             University of Iowa, Iowa City, Iowa                                                                                                

Studentship                                                                                                                                                     1985
             Ciba-Geigy, Basel, Switzerland

Medical Scientist Training Program                                                                                                            1987-1990
             University of Iowa, Iowa City, Iowa

Clinical Investigator Pathway, American Board of Internal Medicine                                                    1992-1994
             Duke University Medical Center, Durham, North Carolina

National Kidney Foundation Research Fellow                                                                                          1995-1996
             Duke University Medical Center, Durham, North Carolina

Assistant Professor of Medicine                                                                                                                  1996-2001
            
University of Louisville, Division of Nephrology
             Louisville, Kentucky

Associate Professor of Medicine                                                                                                                 2001-present
             Medical University of South Carolina, Divison of Nephrology
             Charleston, South Carolina

Section Chief-Nephrology, Director of Dialysis                                                                                         2002-present
            
Ralph H. Johnson VA Medical Center
             Charleston, South Carolina

Administrative Responsibilities

Director, Nephrology Training Program, University of Louisville                                                            2000-2001
Director Nephrology Section, Ralph H Johnson VA Med Center                                                           2002-present
Director of Dialysis, Ralph H Johnson VA Med Center                                                                            2002-present
Secretary-Treasurer, Southern Section AFMR                                                                                         2004-2007
Chair, Southern Section AFMR                                                                                                                   2008-2009

Medical Licensure

South Carolina             Active
Kentucky                       Inactive
North Carolina               Inactive

Board Certification

American Board of Internal Medicine                                                                                                          1993-2003
Nephrology                                                                                                                                                      1998-2008

Awards and Honors

Eagle Scout                                                                                                                                                     1977
National Merit Scholar                                                                                                                                  1978
Alpha Omega Alpha, Medical Honor Society                                                                                             1994
Henry Christian Award for Excellence in Research (AFCR)                                                                    1995
Trainee Investigator Award, Clinical Research Meeting                                                                          1995
Junior Physician-Investigator Award for Excellence in Research (AFMR)                                            2000
Carl W. Gottschalk Research Scholar of the American Society of Nephrology                                   2000
Distinguished Alumni Award, Johnston High School                                                                                2007

Current Grant Support

N01-HV-28181             NIH/NHLBI (J. Arthur Project Leader, PI D. Knapp) 
"Cardiovascular Proteomics Center"                                                                                             9/30/2002-9/29/2009
Role: Project leader for 2D gel technology development, Director of 2D gel core.

VA Merit Grant            Veterans Administration  (PI J. Arthur)                    
“Prognostic Biomarkers in Diabetes”                                                                                              4/01/2008-3/31/2012
Role: Principal Investigator

R01DK080234             NIH/NIDDK (PI J Arthur)         
“Prognostic markers in postoperative acute kidney injury                                                          6/01/2008-5/31/2012
Role: Principal Investigator                  
CRISP Link

P20 RR 17696             NIH/NCRR   (PI S. London)                 
South Carolina COBRE for Oral Health                                                                                        9/30/2002 – 7/31/2008
Role: Mentor

R01AR043727             NIH/NIAMS     (PI M. Petri)     
Hopkins Lupus Cohort                                                                                                                     5/01/2008 -3/31/2013
Role: Principal Investigator of subcontract for proteomic analysis

R01 AR045476            NIH/NIAMS  (PI G. Gilkeson)              
"Nitric oxide in systemic lupus erythematosis".                                                                            3/01/2003-11/29/2008
Role:
Collaborator

VA Career Development Award (PI Janech)                        
"Non-invasive Glomerular Disease Biomarkers."                                                                         6/23/2008-5/30/2011
Role: Mentor

Astellas Pharma US, Inc.      (PI Arthur)                                                                                      2/01/2007-8/01/2008
"A phase 4, randomized, parallel group, multi-center study to assess the safety and efficacy of multiple dosing regimens of iv conivaptan in subjects with euvolemic hyponatremia."
Role: Principal Investigator.                                                                     

Astellas Pharma US, Inc.      (PI Arthur)                                                                                      7/01/2007-12/01/2008
"A phase IIIb, randomized, double-blind, parallel group, multi-center study to assess the efficacy and safety of multiple 30 minute infusions of conivaptan in subjects with euvolemic or hypervolemic hyponatremia."
Role: Principal Investigator.                                                                                  

Arthur Home Page

Arthur Publications

Nephrology Proteomics

SAKInet

SEKDC

MUSC Nephrology

Renal Biomarkers CoEE