Bandyopadhyay, A., J. F. Katz, C. Beeson & A. J. Sant, Relative roles of dominant P1 pocket interactions vs. N-terminal hydrogen bonding interactions for MHC class II:peptide stability. 2007, submitted. 

 

Wisedchaisri, G.; C.J. Chou; M. Wu; C. Roach; A.E. Rice; R.K. Holmes; C. Beeson & W. Hol; Crystal Structures, Metal-activation and DNA-binding Properties of Two-domain IdeR from Mycobacterium tuberculosis.  Biochemistry 2007, 46, 436-47. 

 

Sridharan, V., J. Guichard, R.M. Bailey, H. Kasiganesan, C. Beeson & G.L. Wright, The prolyl hydroxylase oxygen-sensing pathway is cytoprotective and allows maintenance of mitochondrial membrane potential during metabolic inhibition. Am. J. Phys., 2007, 292, C719-28. 

 

McFarland, B.J., J. Katzt, A.J. Sant & C. Beeson, J. Mol. Biol. 2006, 350, 170-183.  Energetics and cooperativity of the hydrogen bonding and anchor interactions that bind peptides to MHC class II protein.


 

Babic, N., N.J. Dovichi & C. Beeson, J. Proteome Res., 2005, 4, 344-348.  ÒThe Effect of High Density Lipoproteins on Protein Expression in Myoblast Cell LinesÓ.

 

Chou, J.C., Wisedchaisri, G., Monfeli, R. R., Oram, D. M. Holmes, R.K., Hol, W.J., & Beeson, C., J. Biol. Chem. 2004, 279, 53554-53561. Functional studies of the Mycobacterium tuberculosis iron dependent regulator protein.

 

Swan, M.K., J. T. G. Solomons, C. Beeson, T. Hansen, P. Schšnheit & C. Davies, J. Biol. Chem. 2003, 278, 47261- 47268.  Structural evidence for a hydride transfer mechanism in phosphoglucose isomerase from Pyrococcus furiosus

 

Beeson, C., J.E. Butrynski, M.J. Hart, C.L Nourigat, D.C. Matthews, O.W. Press, P.D. Senter & I.D. Bernstein.  Bioconj. Chem. 2003, 14, 727-933.  Conditional Cleavable Radioimmunoconjugates- A Novel Approach for the Release of Radioisotopes from Radioimmunoconjugates. 

 

Seamons, A., J. Sutton, D. Bai, E. Baird, N. Bonn, B.F.C. Kafsack, J. Shabanowitz, D.F. Hunt, C. Beeson & J. Goverman.  J. Exp. Med. 2003, 197, 1391-1397.  Competition Between Two MHC Binding Registers In A Single Peptide Processed From Myelin Basic Protein Influences Tolerance And Susceptibility To Autoimmunity. 

 

Reid, P.J., C. Loftus C. & C. Beeson.  Biochemistry 2003, 42, 2441-2448. Evaluating the Potential of Fluorinated Tyrosines as Spectroscopic Probes of Local Protein Environments: A UV Resonance Raman Study.

 

McFarland, B.J., & C. Beeson.  Medicinal Research Reviews 2002, 22, 168-203.  The binding interactions between peptides and proteins of the class II MHC. 

 

Wiley, C. & C. Beeson, Anal. Biochem. 2002, 304, 139-146.  Continuous measurement of glucose utilization in heart myoblasts. 

 

Hart, M.J. & C. Beeson, J. Med. Chem. 2001, 44, 3700-3709. The Utility of Azapeptides as MHC II Protein Ligands for T Cell Activation. 

 

McFarland, B.J., J. Katz, C. Beeson & A. Sant, Proc. Natl. Acad. Sci. USA 2001, 98, 9231-9236.

Energetic asymmetry among hydrogen bonds in MHC class II: peptide complexes.

 

Kennedy, K.J., J.T. Lundquist,, T.L. Simandan,, K.P. Kokko, C. Beeson & T.A. Dix, J. Pept. Res. 2000, 55, 348-358. Design rationale, synthesis, and characterization of non-natural analogs of the cationic amino acids arginine and lysine. 

 

Hodder, PS, C. Beeson & J. Ruzicka, Anal. Chem. 2000, 72,3109-3115. Equilibrium and kinetic measurements of muscarinic receptor antagonism on living cells using bead injection spectroscopy.

 

Lahdesmaki, I., C. Beeson, G. D. Christian & J. Ruzicka, Talanta. 2000, 51, 497-506. Measurement of cellular stimulation through monitoring pH changes by bead injection fluorescence microscopy.

 

Lahdesmaki, I., L.D. Scampavia, C. Beeson & J. Ruzicka, Anal. Chem. 1999, 71, 5248-5252. Detection of oxygen consumption of cultured adherent cells by bead injection spectroscopy.

 

McFarland, B.J., C. Beeson & A.J. Sant, J. Immunol. 1999, 163, 3567-3571.  Cutting edge: A single, essential hydrogen bond controls the stability of peptide-MHC class II complexes. 

 

Sant, A.J., C. Beeson., B.J. McFarland, J. Cao, S. Ceman, P.W. Bryant & S. Wu, Immunol. Rev. 1999, 172, 239-253.  Individual hydrogen bonds play a critical role in MHC class II: peptide interactions: implications for the dynamic aspects of class II trafficking and DM-mediated peptide exchange

 

McFarland, B.J., Sant, A & Beeson, C., J. Am. Chem. Soc. 1999, 48, 11225-11226.  Identification of two distinct structural transitions in the dissociation of peptides from MHC class II proteins. 

 

McFarland, B.J., Sant, A.J., Lybrand, T. & Beeson, C., Biochemistry 1999, 38, 16663-16670.  The Ovalbumin(323-339) peptide binds to the MHC class II I-Ad protein using two functionally distinct registers. 

 

Wei, C.H., Beeson, C., Masucci, M.G. & Levitsky, V., J. Immunol. 1999, 163, 2601-2609.  A partially agonistic peptide acts as a selective inducer of apoptosis in CD8+ CTLs. 

 

Loftus, C., Huseby, E., Gopaul, P., Beeson, C. & Goverman, J., J. Immunol. 1999, 162, 6451-6457.  Highly Cross-reactive T Cell Responses to Myelin Basic Protein Epitopes Reveal a Non-predictable Form of TCR Degeneracy. 

 

Boniface, J.J., J.D. Rabinowitz, C. WŸlfing, J. Hampl, Z. Reich, J.D. Altman, R.M. Kantor, C. Beeson, H.M. McConnell & M.M. Davis,  Immunity 1998, 9, 459-466.  Initiation of signal transduction through the T-cell receptor requires multivalent engagement of MHC ligands. 

 

Harrington, C., A. Paez, A. Hunkapiller, V. Manniko, T. Brabb, M. Ahearn,C. Beeson & J. Goverman, Immunity  1998, 8, 571-580.  Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein. 

 

Rabinowitz, J.D., J. Vacchino, C. Beeson & H.M. McConnell,  J. Am. Chem Soc. 1998, 120, 2464-2473.  Potentiometric measurement of intracellular redox activity. 

 

Lee, C., M.N. Liang, K.M. Tate, J.D. Rabinowitz, C. Beeson, P.P Jones & H.M. McConnell,  J. Exp. Med. 1998, 187, 1505-1516.  Evidence that the autoimmune antigen MBP Ac1-9 binds towards one end of the MHC cleft. 

 

Kennedy, K-J., J.T. Lundquist, T.L. Simandan, C. Beeson & T.A. Dix,  Bioorganic Med. Chem. Lett. 1997, 7, 1937-1940. Asymmetric synthesis of non-natural homologues of lysine. 

 

Rabinowitz, J.D., P. Rigler, C. Carswell-Crumpton, C. Beeson & H.M. McConnell,  Life Sciences 1997, 61, 87-94. Screening for novel drug effects with a microphysiometer: a potent effect of clofilium unrelated to potassium channel blockade. 

 

WŸlfing, C., J.D. Rabinowitz, C. Beeson, M.D. Sjaastad, H.M. McConnell & M.M. Davis,  Immunity  1997, 185, 1815-1825.  Kinetics and extent of T cell activation as measured with the calcium signal. 

 

Rabinowitz, J. D., C. Beeson, C. WŸlfing, K.M. Tate, P.M. Allen, M.M. Davis & H.M. McConnell,  Immunity 1996, 5, 125-135.  Altered T cell receptor ligands trigger a subset of early T cell signals. 

 

Beeson, C., J.D. Rabinowitz, K.M. Tate, I. GŸtgemann, Y. Chien, P.P. Jones, M.M. Davis & H.M. McConnell,  J. Exp. Med. 1996, 184, 777-782.  Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface. 

 

Rabinowitz, J., C. Beeson, D. Lyons, M.M. Davis & H.M. McConnell,  Proc. Natl. Acad. Sci. USA  1996, 93, 1401-1405.  Kinetic discrimination in T cell activation.