Bandyopadhyay,
A., J. F. Katz, C. Beeson & A. J. Sant, Relative
roles of dominant P1 pocket interactions vs. N-terminal hydrogen bonding
interactions for MHC class II:peptide stability. 2007, submitted.
Wisedchaisri,
G.; C.J. Chou; M. Wu; C. Roach; A.E. Rice; R.K. Holmes; C. Beeson & W. Hol;
Crystal Structures, Metal-activation and DNA-binding
Properties of Two-domain IdeR from Mycobacterium tuberculosis. Biochemistry 2007, 46, 436-47.
Sridharan,
V., J. Guichard, R.M. Bailey, H. Kasiganesan, C. Beeson & G.L. Wright, The prolyl hydroxylase oxygen-sensing pathway is cytoprotective
and allows maintenance of mitochondrial membrane potential during metabolic
inhibition. Am. J. Phys., 2007, 292, C719-28.
McFarland,
B.J., J. Katzt, A.J. Sant & C. Beeson, J. Mol. Biol. 2006, 350, 170-183. Energetics and cooperativity of the
hydrogen bonding and anchor interactions that bind peptides to MHC class II
protein.
Babic, N.,
N.J. Dovichi & C. Beeson, J. Proteome Res., 2005, 4, 344-348. ÒThe Effect of High Density
Lipoproteins on Protein Expression in Myoblast Cell LinesÓ.
Chou, J.C., Wisedchaisri, G.,
Monfeli, R. R., Oram, D. M. Holmes, R.K., Hol, W.J., & Beeson, C., J.
Biol. Chem. 2004,
279,
53554-53561. Functional studies of the Mycobacterium
tuberculosis iron dependent regulator protein.
Swan,
M.K., J. T. G. Solomons, C. Beeson, T. Hansen, P. Schšnheit & C. Davies, J.
Biol. Chem. 2003,
278,
47261- 47268. Structural evidence
for a hydride transfer mechanism in phosphoglucose isomerase from Pyrococcus
furiosus
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C., J.E. Butrynski, M.J. Hart, C.L Nourigat, D.C. Matthews, O.W. Press, P.D.
Senter & I.D. Bernstein. Bioconj.
Chem. 2003, 14, 727-933. Conditional Cleavable
Radioimmunoconjugates- A Novel Approach for the Release of Radioisotopes from
Radioimmunoconjugates.
Seamons,
A., J. Sutton, D. Bai, E. Baird, N. Bonn, B.F.C. Kafsack, J. Shabanowitz, D.F.
Hunt, C. Beeson & J. Goverman.
J. Exp. Med. 2003, 197, 1391-1397.
Competition Between Two MHC Binding Registers In A Single Peptide
Processed From Myelin Basic Protein Influences Tolerance And Susceptibility To
Autoimmunity.
Reid,
P.J., C. Loftus C. & C. Beeson.
Biochemistry 2003, 42, 2441-2448. Evaluating the Potential of
Fluorinated Tyrosines as Spectroscopic Probes of Local Protein Environments: A
UV Resonance Raman Study.
McFarland, B.J., & C. Beeson. Medicinal Research Reviews 2002, 22, 168-203. The binding interactions between
peptides and proteins of the class II MHC.
Wiley, C. & C. Beeson, Anal.
Biochem. 2002,
304, 139-146. Continuous
measurement of glucose utilization in heart myoblasts.
Hart, M.J. & C. Beeson, J.
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Activation.
McFarland, B.J., J. Katz, C.
Beeson & A. Sant, Proc. Natl. Acad. Sci. USA 2001, 98, 9231-9236.
Energetic asymmetry among hydrogen bonds in MHC class II:
peptide complexes.
Kennedy,
K.J., J.T. Lundquist,, T.L. Simandan,, K.P. Kokko, C. Beeson & T.A. Dix, J.
Pept. Res. 2000,
55,
348-358. Design rationale, synthesis, and characterization of non-natural
analogs of the cationic amino acids arginine and lysine.
Hodder, PS, C. Beeson & J. Ruzicka, Anal. Chem. 2000, 72,3109-3115. Equilibrium and
kinetic measurements of muscarinic receptor antagonism on living cells using
bead injection spectroscopy.
Lahdesmaki, I., C. Beeson, G. D.
Christian & J. Ruzicka, Talanta. 2000, 51, 497-506. Measurement of cellular stimulation
through monitoring pH changes by bead injection fluorescence microscopy.
Lahdesmaki,
I., L.D. Scampavia, C. Beeson & J. Ruzicka, Anal. Chem. 1999, 71, 5248-5252. Detection of oxygen
consumption of cultured adherent cells by bead injection spectroscopy.
McFarland,
B.J., C. Beeson & A.J. Sant, J. Immunol. 1999, 163, 3567-3571. Cutting edge: A single, essential
hydrogen bond controls the stability of peptide-MHC class II complexes.
Sant,
A.J., C. Beeson., B.J. McFarland, J. Cao, S. Ceman, P.W. Bryant & S. Wu, Immunol.
Rev. 1999, 172, 239-253. Individual hydrogen bonds play a
critical role in MHC class II: peptide interactions: implications for the
dynamic aspects of class II trafficking and DM-mediated peptide exchange
McFarland,
B.J., Sant, A & Beeson, C., J. Am. Chem. Soc. 1999, 48, 11225-11226. Identification of two distinct
structural transitions in the dissociation of peptides from MHC class II
proteins.
McFarland,
B.J., Sant, A.J., Lybrand, T. & Beeson, C., Biochemistry 1999, 38, 16663-16670. The Ovalbumin(323-339) peptide binds to
the MHC class II I-Ad protein using
two functionally distinct registers.
Wei,
C.H., Beeson, C., Masucci, M.G. & Levitsky, V., J. Immunol. 1999, 163, 2601-2609. A partially agonistic peptide acts as a
selective inducer of apoptosis in CD8+ CTLs.
Loftus,
C., Huseby, E., Gopaul, P., Beeson, C. & Goverman, J., J. Immunol. 1999, 162, 6451-6457. Highly Cross-reactive T Cell Responses
to Myelin Basic Protein Epitopes Reveal a Non-predictable Form of TCR
Degeneracy.
Boniface,
J.J., J.D. Rabinowitz, C. WŸlfing, J. Hampl, Z. Reich, J.D. Altman, R.M.
Kantor, C. Beeson, H.M. McConnell & M.M. Davis, Immunity 1998, 9, 459-466.
Initiation of signal transduction through the T-cell receptor requires
multivalent engagement of MHC ligands.
Harrington,
C., A. Paez, A. Hunkapiller, V. Manniko, T. Brabb, M. Ahearn,C. Beeson & J.
Goverman, Immunity 1998, 8, 571-580. Differential tolerance is induced in T
cells recognizing distinct epitopes of myelin basic protein.
Rabinowitz,
J.D., J. Vacchino, C. Beeson & H.M. McConnell, J. Am. Chem Soc. 1998, 120, 2464-2473. Potentiometric measurement of
intracellular redox activity.
Lee, C.,
M.N. Liang, K.M. Tate, J.D. Rabinowitz, C. Beeson, P.P Jones & H.M.
McConnell, J. Exp. Med. 1998, 187, 1505-1516. Evidence that the autoimmune antigen
MBP Ac1-9 binds towards one end of the MHC cleft.
Kennedy,
K-J., J.T. Lundquist, T.L. Simandan, C. Beeson & T.A. Dix, Bioorganic Med. Chem. Lett. 1997, 7, 1937-1940. Asymmetric synthesis
of non-natural homologues of lysine.
Rabinowitz,
J.D., P. Rigler, C. Carswell-Crumpton, C. Beeson & H.M. McConnell, Life Sciences 1997, 61, 87-94. Screening for
novel drug effects with a microphysiometer: a potent effect of clofilium
unrelated to potassium channel blockade.
WŸlfing,
C., J.D. Rabinowitz, C. Beeson, M.D. Sjaastad, H.M. McConnell & M.M. Davis,
Immunity 1997, 185, 1815-1825.
Kinetics and extent of T cell activation as measured with the calcium
signal.
Rabinowitz,
J. D., C. Beeson, C. WŸlfing, K.M. Tate, P.M. Allen, M.M. Davis & H.M.
McConnell, Immunity 1996, 5, 125-135. Altered T cell receptor ligands trigger
a subset of early T cell signals.
Beeson,
C., J.D. Rabinowitz, K.M. Tate, I. GŸtgemann, Y. Chien, P.P. Jones, M.M. Davis
& H.M. McConnell, J. Exp.
Med. 1996, 184, 777-782. Early biochemical signals arise from
low affinity TCR-ligand reactions at the cell-cell interface.
Rabinowitz,
J., C. Beeson, D. Lyons, M.M. Davis & H.M. McConnell, Proc. Natl. Acad. Sci. USA 1996, 93, 1401-1405.
Kinetic discrimination in T cell activation.